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Ubiquinol is a vital compound in the realm of health and longevity. This active, antioxidant form of Coenzyme Q10 (CoQ10) plays a crucial role in cellular energy production and protection against oxidative stress.

In this glossary, we will explore the basic aspects of ubiquinol, including its benefits, sources, and its importance in maintaining optimal health.

What is ubiquinol?

Ubiquinol is the reduced form of Coenzyme Q10, which exists in two states in the body: ubiquinone (oxidized) and ubiquinol (reduced). The human body converts ubiquinone to ubiquinol, which is then utilized in cellular energy production within the mitochondria and acts as a potent antioxidant.

The role of ubiquinol in the body

Ubiquinol is essential for the production of adenosine triphosphate (ATP), the primary energy carrier in cells. It plays a critical role in the electron transport chain within mitochondria, facilitating the transfer of electrons and the generation of energy necessary for cellular functions.

As an antioxidant, ubiquinol protects cells from oxidative damage caused by free radicals. It helps maintain the integrity of cell membranes, proteins, and DNA, thus contributing to overall cellular health and longevity.

Health benefits of ubiquinol

Cardiovascular health

Ubiquinol is known for its benefits to cardiovascular health. It supports heart function by improving energy production in heart cells and reducing oxidative stress. Studies suggest that ubiquinol supplementation can help manage conditions such as hypertension and heart failure.

Brain health

The antioxidant properties of ubiquinol are beneficial for brain health. It helps protect neurons from oxidative damage, which is linked to neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Ubiquinol also supports mitochondrial function in brain cells, promoting cognitive health and function.

Immune support

Ubiquinol plays a role in supporting the immune system. It enhances the function of immune cells by ensuring they have sufficient energy to perform their tasks effectively. Additionally, its antioxidant properties help reduce inflammation, which can bolster the body’s immune response.

Sources of ubiquinol

Ubiquinol can be obtained through diet, though its levels in food are relatively low. Rich dietary sources include:

  • Fatty fish: such as salmon, mackerel and sardines
  • Organ meats: like liver and heart
  • Whole grains: including wheat germ and bran
  • Nuts and seeds: such as peanuts, sesame seeds and pistachios

Given the low ubiquinol content in food, many people opt for supplements to ensure adequate intake. Ubiquinol supplements are widely available and are particularly beneficial for individuals over 40, as the body’s ability to convert ubiquinone to ubiquinol decreases with age.

Ubiquinol vs. ubiquinone

Understanding the difference between ubiquinol and ubiquinone is crucial for effective supplementation:

  • Bioavailability: ubiquinol is more readily absorbed by the body compared to ubiquinone. This makes it a preferred choice for supplementation, especially in older adults.
  • Effectiveness: due to its superior absorption, ubiquinol is often considered more effective at raising blood levels of CoQ10.

Recommended dosage and interactions

The optimal dosage of ubiquinol can vary based on individual health needs and conditions. Generally, a daily dose ranges from 100 to 300 mg. It’s advisable to consult with a healthcare provider to determine the appropriate dosage for specific health goals.

Ubiquinol is generally well-tolerated, with minimal side effects. However, some individuals may experience mild symptoms such as:

  • Nausea
  • Diarrhea
  • Stomach upset

Ubiquinol can interact with certain medications, such as blood thinners and chemotherapy drugs. It’s important to consult with a healthcare provider before starting supplementation, especially if you are taking other medications.

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